logo
  • Downloads
  • Client Login
  • About Us
    • Why DesertSci?
    • Our History
    • Our Approach
    • Our Clients
    • Publications
    • Contact Us
  • Products
    • Proasis4: Protein Structure Database
    • ViewContacts: Non-Covalent Interactions
    • Scorpion: Scoring
    • Viper: Automated Ligand Design
    • Machine Learning: Next Level Scoring
    • ProFusion: Collaboration
    • FELIX: Drug Repurposing
    • Spinifex: Chemical Similarity
    • BMOS: MOS for Large Datasets
  • Software Modules
    • Atom-Based Binding Site Clustering
    • Antibody Structure Based Drug Discovery
    • Antibody Complementarity Determining Regions
    • Antibody-Antigen Interactions
    • Residue Flexibility
    • WaterRank
    • WaterView
  • Modelling Support
  • Licensing
  • Latest News
Home > Software Modules > Antibody-Antigen Interactions

  • Atom-Based Binding Site Clustering
  • Antibody Structure Based Drug Discovery
  • Antibody Complementarity Determining Regions
  • Antibody-Antigen Interactions
  • LIGEX: Rapid Searching of Small Molecules
  • WaterView
  • Residue Flexibility Tool
  • WaterRank

Antibody-Antigen Interactions

The use of modern molecular biologic techniques have accelerated in medicine tremendously in the last decade.

The Antibody-Antigen Interactions Module is an extension of ViewContacts and Scorpion software that assists in the discovery of new biologics. By incorporating our network cooperativity concept into this area of study, we can enhance current knowledge in new and innovative ways.

Biological therapeutics (biologics) present new challenges for computational chemistry. Current researchers typically use force field calculations but these methods do not take account of cooperativity effects. Our methods calculate cooperativity completely differently from other approaches – no other researchers in the field have used this type of approach to investigate hot-spots at protein-protein interfaces.

ViewContacts and Scorpion have been enhanced to incorporate the cooperativity effects specifically for biologics. The software module enables the calculation of non-covalent interactions, water rank scores, and binding affinity scores for protein-protein complexes. This facilitates the study of antigen-antibody interactions, and the rational design of tighter binding antibodies.

Our network approach is unique and provides thought-provoking insights.

To find out more contact us to arrange an evaluation

icon

News & Events

19 Mar 2025

AI in drug discovery: Overcoming the scoring barrier.

19 Mar 2025

Removing friction in Structure-Based Drug Design through advanced molecular dynamics.

22 Sep 2023

Biologics: ProasisAb

10 Jul 2023

ViewContacts2023 – Shipping Now

more articles
image

Looking for FREE Academic Software?

find out more
Logo
  • contact
  • desertsci
  • info@www.desertsci.com

    Ph: +612 8860 6466

    Fax: +612 9680 7520

    © 2011-2025 Desert Scientific Software

    • About Us
    • Our Products
    • Software Modules
    • Modelling Support
    • Licensing
    • News & Events
    Website by The Walk