Proasis system is a strong antibody platform. Now with the latest updates antibody/Fab projects can be more routinely entered and analysed.
Since 2016, DesertSci has invested heavily in development of handling antibody structures. The platform has many powerful analysis tools including:
- automated overlay of antibody chains
- cluster analysis of Fab chains
- automated CDR annotation
- fast CDR search and retrieve methods
- automated CDR-based overlays
- automated CDR clustering
In Proasis2023, new Fab projects can be fully created automatically, with separate sub-projects defined for: antigen, Fab heavy chain, Fab light chain. For existing Fab projects, newly deposited assemblies of Fab complexes can be automatically loaded, with all protein chains correctly assigned to the separate sub-projects.
